Diabetic Renal Disease

Diabetic Renal Disease

1 Diabetes & Endocrine Centre, Mater Dei Hospital, Msida, Malta 2Department of Medicine, University of Malta, Msida, Malta 3 Centre Hospitalier Universitaire Poitiers, Endocrinology, Diabetology, Poitiers, France 4Université de Poitiers, UFR Médecine Pharmacie, Centre d’Investigation Clinique, Poitiers, France 5 CHU de Poitiers, Centre d’Investigation Clinique, Poitiers, France 6 Institut Natio...

Genetics and Diabetic Renal Disease

D iabetic renal disease is still an extremely important and common complication in both type 1 and type 2 diabetic patients. Every clinician and nephrologist knows that diabetic patients constitute a large proportion of clientele in the dialysis unit, perhaps 50% or more, particularly in the U.S. and Japan. The figure is increasing for type 2 diabetes, whereas, encouragingly, a declining number...

The large spectrum of renal disease in diabetic patients

The prevalence of diabetic nephropathy (DN) among diabetic patients seems to be overestimated. Recent studies with renal biopsies show that the incidence of non-diabetic nephropathy (NDN) among diabetic patients is higher than expected. Renal impairment of diabetic patients is frequently attributed to DN without meeting the KDOQI criteria or performing renal biopsy to exclude NDN. In this edito...

Should we be screening for early diabetic renal disease?

Omega-3 fatty acid rich diet prevents diabetic renal disease.

Omega-3 polyunsaturated fatty acids (n-3 PUFA) show beneficial effects in cardiovascular disease, IgA, and diabetic nephropathy; however, the mechanisms underlying these benefits are unknown. The study was performed in male Sprague-Dawley rats randomly divided into four treatment groups: nondiabetic (ND), streptozotocin-induced diabetic (D), diabetic and fed a high n-3 PUFA diet (D+canola), and...